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https://repositorio.ufba.br/handle/ri/5879
metadata.dc.type: | Artigo de Periódico |
Title: | Cognitive dysfunction in congestive heart failure: transcranial Doppler evidence of microembolic etiology |
Other Titles: | Arq Neuropsiquiatr |
Authors: | Jesus, Pedro Antonio Pereira de Melo, Rodrigo Morel Vieira de Reis, Francisco José Farias Borges dos Viana, Leila Castro Lacerda, Amanda Dias, Jesângeli de Sousa Oliveira Filho, Jamary |
metadata.dc.creator: | Jesus, Pedro Antonio Pereira de Melo, Rodrigo Morel Vieira de Reis, Francisco José Farias Borges dos Viana, Leila Castro Lacerda, Amanda Dias, Jesângeli de Sousa Oliveira Filho, Jamary |
Abstract: | Cognitive symptoms are common in patients with congestive heart failure (CHF) and are usually attributed to low cerebral blood flow. In the present study, we aimed to evaluate global cognitive function (Mini Mental State Exam - MMSE) in relation to both cardiac function (evaluated by echocardiogram) and cere b rovascular hemodynamics (evaluated by transcranial Doppler - TCD) in CHF patients. In 83 patients studied, no correlation was found between echocardiographic parameters and MMSE scores. In contrast, a significant correlation was found between right middle cerebral art e ry (RMCA) mean flow velocity and MMSE score (r=0.231 p=0.039), as well as between RMCA pulsatility index and MMSE score (rs= –0.292 p=0.015). After excluding patients with a previous history of stroke, only RMCA pulsatility index c o rrelated with MMSE score (rs=–0,314 p=0,007). The relationship between high cere b rovascular resistance and worse cognitive scores suggest that microembolism may be Responsible for a significant pro p o rtion of cognitive symptoms in CHF patients. |
Keywords: | Transcranial Doppler Congestive heart failure Cognitive dysfunction cerebrovascular disorders |
Publisher: | Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/5879 |
Issue Date: | Jun-2006 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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Jesus, Pedro A.P..pdf | 141,63 kB | Adobe PDF | View/Open |
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