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https://repositorio.ufba.br/handle/ri/5036
metadata.dc.type: | Artigo de Periódico |
Title: | Psychosis During Peginterferon-α2a and Ribavirin Therapy: Case Report |
Other Titles: | The Brazilian Journal of Infectious Diseases |
Authors: | Quarantini, Lucas de Castro Cruz, Simone Cunha Neves, Susana Carolina Batista Paraná, Raymundo Scippa, Ângela Marisa de Aquino Miranda Bressan, Rodrigo Affonseca |
metadata.dc.creator: | Quarantini, Lucas de Castro Cruz, Simone Cunha Neves, Susana Carolina Batista Paraná, Raymundo Scippa, Ângela Marisa de Aquino Miranda Bressan, Rodrigo Affonseca |
Abstract: | Pegylated Interferon-alpha, combined with ribavirin, gives high sustained virological response in patients with hepatitis C virus, an important public health problem and one of the most frequent chronic infectious diseases worldwide. Though it has therapeutic benefits, treatment with IFN-alpha may be complicated by various side effects, especially symptoms of major depression and acute mania. Psychosis is a rare side effect, and its management usually includes discontinuation of IFNalpha. We report a case of psychotic disorder that occurred during therapy with pegylated Interferonalpha given associated with ribavirin. After good response to psychiatric treatment, it became possible to finish the anti-viral therapy. |
Keywords: | Interferon-alpha hepatitis C psychosis |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/5036 |
Issue Date: | 2006 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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a10v10n6.pdf | 37,69 kB | Adobe PDF | View/Open |
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