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metadata.dc.type: | Artigo de Periódico |
Título : | Genetic causes involved in Leishmania Chagasi infection innortheastern - Brazil |
Otros títulos : | Genetics and Molecular Biology |
Autor : | Feitosa, Mary Furlan Azevedo, Eliane Elisa de Souza e Lima, Ângela Maria Krieger, Henrique |
metadata.dc.creator: | Feitosa, Mary Furlan Azevedo, Eliane Elisa de Souza e Lima, Ângela Maria Krieger, Henrique |
Resumen : | A sample of 502 individuals from 94 families from Jacobina, State of Bahia, Brazil, was investigated to determine the causal mechanisms involved in Leishmania chagasi (the causal agent of visceral leishmaniasis in the American hemisphere) infection, as measured by the intradermic reaction to antigens derived from this parasite, using complex segregation analyses. The results showed evidence of a major genetic mechanism acting on infection, with a frequency of a recessive (or additive) susceptibility gene (q) of approximately 0.45. A small multifactorial component (H = 0.29) acting in conjunction with a major recessive gene (q = 0.37) is not ruled out as a concomitant causative factor. |
Editorial : | Sociedade Brasileira de Genética |
URI : | http://www.repositorio.ufba.br/ri/handle/ri/3046 |
Fecha de publicación : | mar-1999 |
Aparece en las colecciones: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Genetics and Molecular Biol....pdf | 216,97 kB | Adobe PDF | Visualizar/Abrir |
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