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metadata.dc.type: | Artigo de Periódico |
Title: | Infiltrating giant cellular blue naevus |
Other Titles: | Journal of Clinical Pathology |
Authors: | Bittencourt, Achilea Candida Lisboa Monteiro, D. A. Pretto, O. J. de |
metadata.dc.creator: | Bittencourt, Achilea Candida Lisboa Monteiro, D. A. Pretto, O. J. de |
Abstract: | Introduction: Cellular blue naevi (CBN) measure 1–2 cm in diameter and affect the dermis, occasionally extending into the subcutaneous fat. The case of a 14-year-old boy with a giant CBN (GCBN) involving the right half of the face, the jugal mucosa and the lower eyelid with a tumour that had infiltrated the bone and the maxillary and ethmoidal sinuses is reported. Methods: Biopsies were taken from the skin, jugal mucosa and maxillary sinus. The following markers were used in the immunohistochemical evaluation: CD34, CD56, HMB-45, anti-S100, A-103, Melan A and MIB-1. Results: The biopsy specimens showed a biphasic pattern affecting the lower dermis, subcutaneous fat, skeletal muscle, bone, jugal mucosa and maxillary sinus, but there was no histological evidence of malignancy. The tumour cells were CD34−, CD56−, HMB45+, anti-S100+ and A-103+. Melan A was focally expressed. No positive MIB-1 cells were identified. Discussion: The present case shows that GCBN may infiltrate deeply, with no evidence of malignancy. |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/15876 |
Issue Date: | 2007 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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J Clin Pathol-2007-Bittencourt-82-4.pdf | 603,9 kB | Adobe PDF | View/Open |
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