Investigação da função coclear na hipofunção tireoidiana: uma revisão sistemática e metanálise

Abstract

Introduction: Several studies relate thyroid hypofunction to changes in auditory system, both in hearing and vestibular aspects. Hearing loss, the most common auditory symptom, may occur in isolation or association with tinnitus and vertigo. Purpose: To investigate the occurrence of cochlear dysfunction in case of thyroid hypofunction. Material and Methods: Study is divided into two stages: the first one is a narrative bibliographic review on thyroid function and its relationship with hearing; the second is a systematic review and meta-analysis of articles on the subject; research was carried out in electronic databases Medline/PubMed, LILACS, Embase, Scopus, SciELO and Science Direct. Inclusion of articles in systematic review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Results: From the 17.061 articles that were initially identified in all databases, 17.049 were excluded for not achieving the research objective and 12 articles were considered eligible to the review. In 75% of the studies there was no change in cochlear functi