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dc.contributor.authorXavier, Flávia Caló de Aquino-
dc.contributor.authorRodini, Camila Oliveira-
dc.contributor.authorRamalho, Luciana Maria Pedreira-
dc.contributor.authorSarmento, Viviane Almeida-
dc.contributor.authorNunes, Fabio Daumas-
dc.creatorXavier, Flávia Caló de Aquino-
dc.creatorRodini, Camila Oliveira-
dc.creatorRamalho, Luciana Maria Pedreira-
dc.creatorSarmento, Viviane Almeida-
dc.creatorNunes, Fabio Daumas-
dc.date.accessioned2012-06-04T19:41:16Z-
dc.date.issued2008-
dc.identifier.issn1079-2104-
dc.identifier.urihttp://www.repositorio.ufba.br/ri/handle/ri/6071-
dc.descriptionAcesso restrito: Texto completo. p. 403-410pt_BR
dc.description.abstractClear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor associated with aggressive clinical behavior, metastasis, and low survival. We report a case of CCOC affecting the mandible of a 39-year-old man. The tumor presented a biphasic pattern composed of clear cell nests intermingled with eosinophilic cells and separated by collagenous stroma. Immunoreactivity to cytokeratin (CK), specifically AE1/AE3 and CK 8, 14, 18, and 19 was found, as well as to epithelial membrane antigen (EMA). The tumor cells were negative for S100 protein, CK 13, vimentin, smooth muscle actin, laminin and type IV collagen. Low labeling indices for the proliferation markers Ki-67 and proliferating cell nuclear antigen and to p53 protein might predict a favorable prognosis for the lesion. A surgical resection was performed, followed by adjuvant radiotherapy. A 2-year follow-up has shown no signs of recurrence. The significance of histochemical and immunohistochemical resources in the correct diagnosis of CCOC is analyzed. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:403-10)pt_BR
dc.language.isoenpt_BR
dc.sourcehttp://dx.doi.org/10.1016/j.tripleo.2008.03.010pt_BR
dc.titleClear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosispt_BR
dc.title.alternativeOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontologypt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 106, n. 3pt_BR
dc.embargo.liftdate10000-01-01-
Aparece en las colecciones: Artigo Publicado em Periódico (Faculdade de Odontologia)

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